This exceptional mixed-use commercial opportunity offers a versatile office building paired with an on-site residential duplex in a prime San Antonio location. Situated on approximately 5.24 acres, the property features an expansive 29,469-square-foot single-story layout designed to accommodate a wide variety of business, administrative, institutional, or professional uses. Fronting West Avenue with excellent visibility and convenient access to Loop 410 and I-10, the site offers ideal connectivity for corporate offices, medical and wellness practices, education or training facilities, or other commercial operations permitted under C-2 zoning. The building comes partially furnished and equipped, allowing for immediate occupancy with reduced startup or build-out costs. Generous floor areas and flexible interior spaces create opportunities for efficient office planning, collaborative work environments, or specialty business needs. An additional 2,027-square-foot duplex on the property provides valuable flexibility for on-site staff or leadership housing, corporate lodging, or supplemental rental income. With modern infrastructure, strategic location, and nearly five acres offering future growth or redevelopment potential, this property presents a rare investment or owner-user opportunity in one of San Antonio's most accessible commercial corridors. Schedule a showing today!

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Listed by Eddie Karam of Compass RE Texas,LLC ((512) 969-8527)

Listings courtesy of Unlock MLS as distributed by MLS GRID. Based on information submitted to the MLS GRID as of May 25, 2026 5:13 AM EDT. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information. IDX information is provided exclusively for consumers’ personal noncommercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The data is deemed reliable but is not guaranteed by MLS GRID. The use of the MLS GRID Data may be subject to an end user license agreement.

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